Where Does Epinephrine Elute on a CAX Column?

Purpose

This article explains the retention times of epinephrine on a CAX column and how epinephrine interacts with Norepinephrine.

Solution

 Under standard separation conditions, Epi has a retention time of 5.9mins. The peak is not well resolved from norepinephrine which elutes at 5.4mins.  Slight variations may arise based on slight differences in mobile phase composition, column/precolumn age, and other factors.

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